Entamoeba histolytica Notes | Basic Science Series

Entamoeba histolytica Notes | Basic Science Series

The ectoplasm is the outer, more gel-like region of the amoeba's cytoplasm. It lies just beneath the cell's plasma membrane or cell membrane. The ectoplasm is denser and more viscous compared to the endoplasm, giving it a gelatinous appearance.

The endoplasm is the inner, more fluid-like region of the amoeba's cytoplasm. It is located closer to the cell's central nucleus and contains various organelles, such as the mitochondria, food vacuoles, and other structures involved in cellular metabolism and digestion.

Pseudopodia: Pseudopodia are temporary extensions of the cytoplasm that the trophozoite uses for movement and engulfing food. These pseudopodia project outwards, anchor to a substrate, and then pull the rest of the cell forward.

karyosome refers to the structure found within the nucleus of the cell. The nucleus is the central organelle responsible for containing the genetic material (DNA) of the cell. The karyosome is a condensed, rounded mass or cluster of chromatin material within the nucleus. Chromatin consists of DNA, histone proteins, and other associated protein

In amoeba, chromatin refers to the complex of DNA and associated proteins found within the nucleus of the cell. Chromatin is the form in which the genetic material is organized and packaged in eukaryotic cells like amoeba.

Food vacuole is a membrane-bound organelle involved in the process of intracellular digestion. Food vacuoles are essential for the nutrition of amoebae and other phagocytic organisms.

Ingested RBCs: Entamoeba histolytica is known for ingesting red blood cells (RBCs) from the host's intestinal lining. This characteristic gives rise to the term "amebic trophozoite with ingested RBCs," which can be seen in diagnostic samples.

Cyst Formation: Under certain conditions, trophozoites can transform into cysts, the dormant and resistant form of the parasite. Cysts are the stage responsible for the transmission of the parasite from one host to another through contaminated food or water.

Entamoeba histolytica | Structure and Function | Parasitology | Basic Science Series Entamoeba histolytica, Amoebiasis, Trophozoite, Cyst, Eukaryotic organism, Amoebozoa, Transmission, Fecal contamination, Poor sanitation, Invasive intestinal disease, Amoebic dysentery, Colitis, Pseudopodia, Cytoplasm, Nucleus, Karyosome, Chromatin, Food vacuole, Ingested RBCs, Dormant stage.

• Entamoeba histolytica is a single-celled, eukaryotic organism belonging to the phylum Amoebozoa. It can exist in two forms: the active, motile trophozoite stage, and the dormant, non-motile cyst stage. The parasite is transmitted through contaminated food or water, facilitated by poor sanitation and hygiene practices.

• E. histolytica can cause a range of diseases, from asymptomatic colonization to invasive amoebiasis, resulting in amoebic dysentery or colitis. The trophozoite stage is responsible for causing the invasive intestinal and extraintestinal disease.

• The trophozoite of E. histolytica is typically 10 to 60 micrometers in diameter and has an irregular, ameboid shape. It can change its shape and move using pseudopodia (temporary extensions of its cytoplasm). The cytoplasm contains various organelles responsible for metabolic activities and digestion, with ectoplasm being the outer gel-like region and endoplasm being the inner fluid-like region.

• The trophozoite contains a single, large, and centrally located nucleus with a karyosome, which is a condensed cluster of chromatin material. It ingests red blood cells from the host's intestinal lining.

• Under certain conditions, trophozoites can transform into cysts, the dormant and resistant form of the parasite, responsible for its transmission to new hosts through contaminated food or water. WhatsApp group: https://chat.whatsapp.com/HTXQC1Ax2qfKYa3MrZiMeD Twitter: https://twitter.com/basic_series Facebook Group: https://www.facebook.com/groups/742235929758671 LinkedIn: https://www.linkedin.com/in/basic-science-series-a54439208/ Instagram: https://www.instagram.com/basic_science_series/ Support my work at https://www.patreon.com/user?u=37177596

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